{"id":6113,"date":"2022-11-16T10:28:18","date_gmt":"2022-11-16T18:28:18","guid":{"rendered":"https:\/\/cms.helloklarity.com\/?p=6113"},"modified":"2023-12-20T11:53:10","modified_gmt":"2023-12-20T19:53:10","slug":"amoxapine-vs-amitriptyline","status":"publish","type":"post","link":"https:\/\/cms.helloklarity.com\/post\/amoxapine-vs-amitriptyline\/","title":{"rendered":"Amoxapine vs. Amitriptyline\u00a0"},"content":{"rendered":"\n<p>Though amoxapine and amitriptyline have similar effects on the body and brain, one may work better for you depending on your depression symptoms, body chemistry, and contraindicated medications or conditions. The comparison guide below can help you have a more informed discussion with your healthcare provider when deciding if you should start antidepressants.&nbsp;<\/p>\n\n\n\n<p>If you are interested in treating your depression with medication, <a href=\"https:\/\/care.klarityadhd.com\/assessment\/get-started\" target=\"_blank\" rel=\"noopener\">schedule an appointment<\/a> on Klarity today. We\u2019ll match you with a healthcare provider who can evaluate your symptoms through <a href=\"https:\/\/www.klarityadhd.com\/depression\/\" target=\"_blank\" rel=\"noopener\">online depression treatment<\/a> to determine if Amoxapine, Amitriptyline, or another form of antidepressant is right for you.&nbsp;<\/p>\n\n\n\n<table id=\"tablepress-61\" class=\"tablepress tablepress-id-61 tablepress-responsive\">\n<thead>\n<tr class=\"row-1 odd\">\n\t<th class=\"column-1\"><\/th><th class=\"column-2\">Amitriptyline<\/th><th class=\"column-3\">Amoxapine<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-hover\">\n<tr class=\"row-2 even\">\n\t<td class=\"column-1\"><strong>Drug Class<\/strong><\/td><td class=\"column-2\">Tricyclic antidepressant<\/td><td class=\"column-3\">Tricyclic antidepressant<br \/>\r\n<br \/>\r\n<\/td>\n<\/tr>\n<tr class=\"row-3 odd\">\n\t<td class=\"column-1\"><strong>Brand \/ Generic Status<\/strong><\/td><td class=\"column-2\">Generic (Brand name: Elavil)<\/td><td class=\"column-3\">Generic (Brand name: Asendin)<br \/>\r\n<br \/>\r\n<\/td>\n<\/tr>\n<tr class=\"row-4 even\">\n\t<td class=\"column-1\"><strong>Form(s) of the Drug<\/strong><\/td><td class=\"column-2\">\u2022 Tablets<br \/>\n\u2022 Yellow, fruit-flavored liquid suspension<br \/>\n<\/td><td class=\"column-3\">Immediate-release color-coded tablets<\/td>\n<\/tr>\n<tr class=\"row-5 odd\">\n\t<td class=\"column-1\"><strong>Standard Dosage<\/strong><\/td><td class=\"column-2\">Tablets: <br \/>\n\u2022 10mg<br \/>\n\u2022 25mg<br \/>\n\u2022 50mg<br \/>\n\u2022 75mg<br \/>\n\u2022 100mg<br \/>\n\u2022 150mg<br \/>\n<br \/>\nLiquid suspension:<br \/>\n\u2022 10mg per dose<br \/>\n<\/td><td class=\"column-3\">Immediate-release color-coded tablets: <br \/>\r\n\u2022 25mg: white<br \/>\r\n\u2022 50mg: orange<br \/>\r\n\u2022 100mg: blue<br \/>\r\n\u2022 150mg: light orange<br \/>\r\n<\/td>\n<\/tr>\n<tr class=\"row-6 even\">\n\t<td class=\"column-1\"><strong>Conditions Treated<\/strong><\/td><td class=\"column-2\">FDA-approved uses:<br \/>\n\u2022 Major depressive disorder<br \/>\n\u2022 Anxiety disorder<br \/>\n\u2022 OCD<br \/>\n<br \/>\nOff-label uses: <br \/>\n\u2022 Chronic fibromyalgia pain<br \/>\n\u2022 Nerve pain <br \/>\n\u2022 Sleep disorders <br \/>\n\u2022 Bladder pain <br \/>\n\u2022 Irritable bowel syndrome<br \/>\n<br \/>\n<\/td><td class=\"column-3\">FDA-approved: <br \/>\r\n\u2022 Depression with psychotic features<br \/>\r\n\u2022 Nerve pain<br \/>\r\n<br \/>\r\nOff-label: <br \/>\r\n\u2022 Difficulty sleeping<br \/>\r\n<\/td>\n<\/tr>\n<tr class=\"row-7 odd\">\n\t<td class=\"column-1\"><strong>Cost<\/strong><\/td><td class=\"column-2\">Generic form (amitriptyline):<br \/>\n\u2022 $140 to $300 for a 30-day supply<br \/>\n\u2022 $4 for a 30-day supply with insurance or coupon card<br \/>\n<\/td><td class=\"column-3\">Generic (amoxapine): <br \/>\r\n\u2022 $20 to $36 for a 30-day supply<br \/>\r\n<br \/>\r\nBrand name: <br \/>\r\n\u2022 Brand name formula not available for Rx<br \/>\r\n<br \/>\r\n<\/td>\n<\/tr>\n<tr class=\"row-8 even\">\n\t<td class=\"column-1\"><strong>Side-Effects<\/strong><\/td><td class=\"column-2\">Common side effects:<br \/>\n\u2022 Drowsiness, blurred vision<br \/>\n\u2022 Dry mouth, constipation <br \/>\n\u2022 Weight gain<br \/>\n\u2022 Difficulty urinating <br \/>\n\u2022 Persistent heartburn<br \/>\n\u2022 Easy bruising or bleeding<br \/>\n\u2022 Black stools<br \/>\n\u2022 Vomit that looks like coffee grounds  <br \/>\n\u2022 Muscle spasms, shaking<br \/>\n\u2022 Severe abdominal pain <br \/>\n\u2022 Decreased libido<br \/>\n\u2022 Enlarged or painful breasts <br \/>\n\u2022 Severe dizziness, fainting, seizures, confusion <br \/>\n\u2022 Eye pain, redness or swelling, vision changes <br \/>\n\u2022 Sweating <br \/>\n<\/td><td class=\"column-3\">Common side effects: <br \/>\r\n\u2022 Sedation or drowsiness<br \/>\r\n\u2022 Dry mouth<br \/>\r\n\u2022 Constipation, nausea <br \/>\r\n\u2022 Fatigue or weakness <br \/>\r\n\u2022 Blurred vision <br \/>\r\n\u2022 Anxiety or restlessness<br \/>\r\n\u2022 Insomnia or difficulty sleeping <br \/>\r\n\u2022 Confusion or altered consciousness<br \/>\r\n\u2022 Palpitations or changes in EKG patterns <br \/>\r\n\u2022 Tremors <br \/>\r\n\u2022 Increased appetite causing changes in weight over time <br \/>\r\n<br \/>\r\nSerious side effects <br \/>\r\n\u2022 Signs of Neuroleptic \u2022 Malignant Syndrome (NMS)<br \/>\r\n\u2022 Serotonin syndrome<br \/>\r\n\u2022 Increased suicidal thoughts or self-harm behaviors<br \/>\r\n<br \/>\r\n<\/td>\n<\/tr>\n<tr class=\"row-9 odd\">\n\t<td class=\"column-1\"><strong>Warnings For Use<\/strong><\/td><td class=\"column-2\">Drug interactions:<br \/>\n\u2022 Quinidine<br \/>\n\u2022 Cimetidine <br \/>\n\u2022 Many other antidepressants: SSRIs<br \/>\n\u2022 Type 1C antiarrhythmics <br \/>\n\u2022 MAO inhibitors <br \/>\n\u2022 Thyroid medication <br \/>\n\u2022 Alcohol, barbiturates and other CNS depressants <br \/>\n\u2022 Anticholinergic drugs  <br \/>\n<\/td><td class=\"column-3\">Drug interactions<br \/>\r\n\u2022 Other anticholinergic medications<br \/>\r\n\u2022 Blood pressure medication <br \/>\r\n\u2022 Alcohol and barbiturates<br \/>\r\n\u2022 MAOIs<br \/>\r\n\u2022 SSRIs<br \/>\r\n\u2022 Thyroid supplements<br \/>\r\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-61 from cache -->\n\n\n\n<h2 class=\"wp-block-heading\">Amitriptyline and Amoxapine Are the Same Class of Drugs (Tricyclics)<\/h2>\n\n\n\n<p>Tricyclic antidepressants (TCAs) are among the earliest antidepressants developed. Though many physicians opt for more modern antidepressants with fewer side effects, like SSRIs or SNRIs,&nbsp; tricyclic medications are sometimes prescribed if other formulas prove ineffective.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What Are Tricyclics?<\/h3>\n\n\n\n<p>Tricyclic medications are named for their chemical structure, which contains three rings. Both of these medications are tricyclic-class antidepressants that work by preventing norepinephrine and serotonin reuptake in the brain. This makes both of these neurotransmitters more available in the body and evens out chemical imbalances that cause major depression.<\/p>\n\n\n\n<p>Amoxapine and amitriptyline may be among the most commonly prescribed tricyclic antidepressants. However, critical differences may make one a better choice for you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Amitriptyline and Amoxapine Are Both Used To Treat Major Depressive Disorder<\/h2>\n\n\n\n<p>According to <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/depression\/symptoms-causes\/syc-20356007\" target=\"_blank\" rel=\"noopener\">MayoClinic<\/a>, major depressive disorder\u2014also called clinical depression\u2014is a pervasive feeling of sadness, numbness, or loss of interest in daily life. You may have difficulty caring for yourself or maintaining relationships, trouble sleeping, little to no appetite, or even angry outbursts fueled by frustration and fatigue.&nbsp;<\/p>\n\n\n\n<p>While depression often results from external events, tricyclic antidepressants like Amitriptyline and amoxapine are most often prescribed to treat endogenous, or internalized, depression. This kind of depression happens when the brain doesn\u2019t produce enough serotonin and norepinephrine.&nbsp;<\/p>\n\n\n\n<p>Tricyclic medications are among the most effective at increasing these neurotransmitters in the brain and alleviating the symptoms of major depression.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What Else Does Amitriptyline Treat?<\/h3>\n\n\n\n<p>Amitriptyline, or its brand name Elavil, is also prescribed to treat insomnia and nerve pain. It\u2019s usually prescribed in much lower doses to treat these conditions, between 10mg and 25mg. However, those taking it for insomnia may experience daytime drowsiness.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Off-label Uses for Amitriptyline<\/h4>\n\n\n\n<p>Healthcare providers sometimes prescribe medications off-label to treat conditions outside the FDA-approved use. This is a common practice, especially if other medications don\u2019t work or are contraindicated for certain individuals.&nbsp;<\/p>\n\n\n\n<p>Amitriptyline can be prescribed off-label to treat:&nbsp;<\/p>\n\n\n\n<ul>\n<li>Fibromyalgia<\/li>\n\n\n\n<li>Migraines and chronic headaches<\/li>\n\n\n\n<li>Bladder pain<\/li>\n\n\n\n<li>Irritable bowel syndrome<\/li>\n\n\n\n<li>Chronic fatigue syndrome<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">What Else Does Amoxapine Treat?<\/h3>\n\n\n\n<p>Amoxapine\u2014brand-name Asendin\u2014is only FDA-approved to treat clinical or major depression. All other uses are off-label.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Off-label Uses for Amoxapine<\/h4>\n\n\n\n<p>Medical professionals may prescribe amoxapine off-label to treat:&nbsp;<\/p>\n\n\n\n<ul>\n<li>Bipolar depressive phases<\/li>\n\n\n\n<li>Anxiety<\/li>\n\n\n\n<li>Insomnia<\/li>\n\n\n\n<li>Neuropathic (nerve) pain<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What is Amoxapine?<\/h2>\n\n\n\n<p>Amoxapine is the generic name for Adensin, a tricyclic antidepressant frequently prescribed to treat depression caused by an internal chemical imbalance. Because of its high likelihood of side effects and contraindications, it\u2019s often used as a last resort for those resistant to other types of antidepressants.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Doses, Dosage Form, and Side Effects of Amoxapine<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Common Amoxapine Doses and Forms<\/h3>\n\n\n\n<p>Amoxapine is available as tablets color-coded according to dosage, as follows:&nbsp;<\/p>\n\n\n\n<ul>\n<li>25mg: white<\/li>\n\n\n\n<li>50mg: orange<\/li>\n\n\n\n<li>100mg: blue<\/li>\n\n\n\n<li>150mg: light orange<\/li>\n<\/ul>\n\n\n\n<p>Dosage usually begins at 25mg. If the patient tolerates the medication well, the dosage is gradually increased to between 200 and 300mg. Some individuals may need up to 400mg, but no prescription should be higher than this.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Common Amoxapine Side Effects<\/h3>\n\n\n\n<p>The most common side effects of amoxapine include:&nbsp;<\/p>\n\n\n\n<ul>\n<li>Drowsiness or fatigue<\/li>\n\n\n\n<li>Dry mouth<\/li>\n\n\n\n<li>Constipation<\/li>\n\n\n\n<li>Vision changes<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Common Amoxapine Drug Interactions<\/h3>\n\n\n\n<p>Amoxapine can interact adversely with many drugs and supplements, including:&nbsp;<\/p>\n\n\n\n<ul>\n<li>Monoamine oxidase inhibitors (MAOIs)<\/li>\n\n\n\n<li>Certain asthma medications&nbsp;<\/li>\n\n\n\n<li>Blood pressure drugs<\/li>\n\n\n\n<li>Motion sickness medications<\/li>\n\n\n\n<li>Antipsychotics<\/li>\n\n\n\n<li>Other antidepressants<\/li>\n\n\n\n<li>Thyroid supplements<\/li>\n\n\n\n<li>Opioid-based prescriptions<\/li>\n\n\n\n<li>Anxiety medications<\/li>\n\n\n\n<li>Sleeping pills<\/li>\n\n\n\n<li>Muscle relaxers<\/li>\n\n\n\n<li>Antihistamines<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">How Much Does Amoxapine Cost?<\/h3>\n\n\n\n<p>Since amoxapine is a generic medication, it\u2019s available at lower prices. Depending on your insurance coverage and available discounts, a one-month supply may cost between $71 and $20.<\/p>\n\n\n\t\t<div data-elementor-type=\"page\" data-elementor-id=\"15401\" class=\"elementor elementor-15401\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c521b1f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c521b1f\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1e5f769\" data-id=\"1e5f769\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-8537e6b elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8537e6b\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-f020c0d\" data-id=\"f020c0d\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2478e2a elementor-widget__width-auto elementor-widget elementor-widget-heading\" data-id=\"2478e2a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.19.0 - 07-02-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-large\">Licensed providers on Klarity provide personalized treatment. \nFind a provider that matches your needs and preferences.<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-87df69e elementor-widget elementor-widget-spacer\" data-id=\"87df69e\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.19.0 - 07-02-2024 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container{height:100%;width:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty,.e-con>.elementor-widget-spacer.elementor-widget-empty{position:relative;min-height:22px;min-width:22px}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon,.e-con>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon{position:absolute;top:0;bottom:0;left:0;right:0;margin:auto;padding:0;width:22px;height:22px}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-76f1234 elementor-widget-tablet__width-inherit elementor-tablet-align-center elementor-align-center elementor-widget__width-auto elementor-widget elementor-widget-button\" data-id=\"76f1234\" data-element_type=\"widget\" data-settings=\"{&quot;sticky&quot;:&quot;top&quot;,&quot;sticky_on&quot;:[&quot;mobile&quot;],&quot;sticky_offset_mobile&quot;:0,&quot;sticky_effects_offset_mobile&quot;:0,&quot;sticky_offset&quot;:0,&quot;sticky_effects_offset&quot;:0}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-md\" href=\"https:\/\/care.helloklarity.com\/assessment\/get-started?utm_source=blog&#038;utm_medium=cta&#038;utm_campaign=blue\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">Find a provider<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t\n\n\n\n<h2 class=\"wp-block-heading\">What is Amitriptyline?<\/h2>\n\n\n\n<p>Amitriptyline is the generic name for Elavil, which is also a tricyclic antidepressant. It has many of the same effects and uses as amoxapine, though it has more bothersome side effects than amoxapine. It can also be used to treat nerve pain and insomnia.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Doses, Dosage Form, and Side Effects of Amitriptyline<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Common Amitriptyline Doses and Forms<\/h3>\n\n\n\n<p>Amitriptyline comes in tablets that are color-coded to indicate the dosage, as follows:&nbsp;<\/p>\n\n\n\n<ul>\n<li>10mg: blue, round<\/li>\n\n\n\n<li>25mg: yellow, round<\/li>\n\n\n\n<li>50mg: beige, round<\/li>\n\n\n\n<li>75mg: orange, round<\/li>\n\n\n\n<li>100mg: mauve, round<\/li>\n\n\n\n<li>150mg: blue, capsule-shaped<\/li>\n<\/ul>\n\n\n\n<p>Patients typically start with a dose of 20 to 50mg per day\u2014to be taken at bedtime\u2014and gradually increase their dosage to between 150 and 300mg per day. The dosage should not exceed 300mg.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Common Amitriptyline Side Effects<\/h3>\n\n\n\n<p>Side effects result from your body acclimating to a new medication. Many are temporary and diminish or disappear entirely after a few weeks. However, if your side effects become debilitating, contact your healthcare provider immediately.<\/p>\n\n\n\n<p>The most common side effects of amitriptyline include:&nbsp;<\/p>\n\n\n\n<ul>\n<li>Drowsiness or dizziness<\/li>\n\n\n\n<li>Dry mouth<\/li>\n\n\n\n<li>Blurred vision<\/li>\n\n\n\n<li>Constipation or difficulty urinating<\/li>\n\n\n\n<li>Weight gain<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Common Amitriptyline Drug Interactions<\/h3>\n\n\n\n<p>Drug interactions occur when one medication interacts adversely with other medications or supplements you\u2019re already taking. Amitriptyline may increase the effects of your other medications or vice versa, placing your health at risk.&nbsp;<\/p>\n\n\n\n<p>Amitriptyline is contraindicated for combination with many drugs and supplements, including:&nbsp;<\/p>\n\n\n\n<ul>\n<li>Monoamine oxidase inhibitors (MAOIs)<\/li>\n\n\n\n<li>Antiplatelet drugs (e.g., NSAIDs)<\/li>\n\n\n\n<li>Blood thinners<\/li>\n\n\n\n<li>Blood pressure medications<\/li>\n\n\n\n<li>Certain asthma prescriptions<\/li>\n\n\n\n<li>Drugs that affect heart rate<\/li>\n\n\n\n<li>Other antidepressants<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">How Much Does Amitriptyline Cost?<\/h3>\n\n\n\n<p>Because it\u2019s the generic version of Elavil, amitriptyline is relatively inexpensive. Depending on your insurance coverage and available discounts, a 30-day supply may cost between $25 and $4.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Do I Need A Prescription for Amitriptyline or Amoxapine?<\/h2>\n\n\n\n<p>Yes, all tricyclic drugs used to treat major depression are controlled substances and require a prescription to take them. Individuals taking this class of antidepressants are also usually closely monitored by their healthcare providers to ensure they\u2019re tolerating the medication well and are not experiencing cognitive side effects like suicidal ideation.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Tricyclic Side Effects<\/h2>\n\n\n\n<p>Though every tricyclic drug is a little different, they all have similar effects on the brain and share specific side effects. Some of these side effects include:&nbsp;<\/p>\n\n\n\n<ul>\n<li>Weight loss<\/li>\n\n\n\n<li>Excessive sweating<\/li>\n\n\n\n<li>Tremor<\/li>\n\n\n\n<li>Sexual dysfunction<\/li>\n<\/ul>\n\n\n\n<p>These drugs may also lead to more significant concerns, such as those described below.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What is Serotonin Syndrome?<\/h3>\n\n\n\n<p>Serotonin is a neurotransmitter that regulates everything from mood and sleep cycles to wound healing and bone health. Having the right amount is crucial to optimum health. However, antidepressants can sometimes increase serotonin in the brain to dangerous levels, resulting in serotonin syndrome.&nbsp;<\/p>\n\n\n\n<p>Common symptoms include anxiety, nausea, tremors, irregular heartbeat, or seizures. Left untreated, it can be fatal. If you experience any of these symptoms, contact your healthcare provider immediately.&nbsp;&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Pregnancy and Breastfeeding on Tricyclics<\/h3>\n\n\n\n<p>Tricyclics may harm your baby if you\u2019re pregnant or breastfeeding while taking these medications. Neonatal infants exposed to these drugs in the womb may be born with a dependency on them, which places their health at risk. These medications are also metabolized into breast milk and may have unknown effects on breastfeeding infants and children.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Increased Bleeding Risk With Tricyclics<\/h3>\n\n\n\n<p>While tricyclics may not be indicated for bleeding risk when taken alone, they can interact with other medications and increase the likelihood of excessive bleeding. This is especially true if you take blood pressure medications or other antidepressants.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Find the Right Depression Medication For You With Help From Klarity<\/h2>\n\n\n\n<p>If you have major depression and believe that antidepressants could help, <a href=\"https:\/\/care.klarityadhd.com\/assessment\/get-started\" target=\"_blank\" rel=\"noopener\">find a provider<\/a> on Klarity today for simple and affordable <a href=\"https:\/\/www.klarityadhd.com\/depression\/\" target=\"_blank\" rel=\"noopener\">online depression treatment<\/a>. In just 48 hours, you\u2019ll be speaking with a medical professional virtually to discuss your symptoms and determine if medications like Amoxapine, Amitriptyline are right for you.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Amoxapine and Amitriptyline Frequently Asked Questions<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Are Amoxapine, Amitriptyline, and other Tricyclics the same thing?<\/h3>\n\n\n\n<p>Though all tricyclic medications are in the same class of drugs and work similarly in the body, they\u2019re not all the same drug. Each formula is a little different to help ensure there are safe options for as many people as possible.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Why is Amoxapine an off-label treatment for anxiety?<\/h3>\n\n\n\n<p>Amoxapine has proven effective in alleviating anxiety disorder, but it hasn\u2019t yet undergone the rigorous testing needed to be FDA-approved for that use.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What\u2019s better for anxiety? Amoxapine or Amitriptyline?<\/h3>\n\n\n\n<p>Both medications can alleviate the symptoms of anxiety. However, amoxapine is prescribed more often because it\u2019s less likely to cause daytime drowsiness than amitriptyline.&nbsp;&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What\u2019s better for depression? Amoxapine or Amitriptyline?<\/h3>\n\n\n\n<p>Which medication is right for you depends on several factors, including other medications or conditions you may have. Your healthcare provider can review your medical history with you and help you decide which medication to try.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Can I drive on antidepressants like Amoxapine or Amitriptyline?<\/h3>\n\n\n\n<p>You should avoid driving or operating other heavy machinery until you know how these medications will affect you. They may cause daytime sleepiness, which causes an impaired ability to concentrate.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Can I drink alcohol on Amoxapine or Amitriptyline?<\/h3>\n\n\n\n<p>No. Drinking on TCAs is much different than other antidepressants, so be sure to speak with your medical provider about alcohol usage when you\u2019re taking these medications.. Alcohol increases the effects of these drugs and may make it hazardous to drive or cause a fatal chemical reaction in the brain.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Does it matter what time of day I take Amoxapine or Amitriptyline?<\/h3>\n\n\n\n<p>Since both medications may cause mild to moderate drowsiness, it\u2019s best to take them at night, an hour or so before you intend to go to bed.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-layout-1 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p>Sources:&nbsp;<\/p>\n\n\n\n<p>\u201cAmoxapine.\u201d <em>Rx List.&nbsp;<\/em><\/p>\n\n\n\n<p><a href=\"https:\/\/www.rxlist.com\/amoxapine-drug.htm#description\" target=\"_blank\" rel=\"noopener\">https:\/\/www.rxlist.com\/amoxapine-drug.htm#description<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.rxlist.com\/script\/main\/art.asp?articlekey=81326\" target=\"_blank\" rel=\"noopener\">John P. Cunha<\/a>. \u201cElavil.\u201d <em>Rx List.&nbsp;<\/em><\/p>\n\n\n\n<p><a href=\"https:\/\/www.rxlist.com\/elavil-drug.htm#description\" target=\"_blank\" rel=\"noopener\">https:\/\/www.rxlist.com\/elavil-drug.htm#description<\/a><\/p>\n\n\n\n<p>Sanjai Sinha. \u201cAmitriptyline.\u201d <em>Drugs.com.&nbsp;<\/em><\/p>\n\n\n\n<p><a href=\"https:\/\/www.drugs.com\/amitriptyline.html#side-effects\" target=\"_blank\" rel=\"noopener\">https:\/\/www.drugs.com\/amitriptyline.html#side-effects<\/a><\/p>\n\n\n\n<p>\u201cAsendin (Oral).\u201d <em>Drugs.com<\/em>.&nbsp;<\/p>\n\n\n\n<p><a href=\"https:\/\/www.drugs.com\/cons\/asendin.html\" target=\"_blank\" rel=\"noopener\">https:\/\/www.drugs.com\/cons\/asendin.html<\/a><\/p>\n\n\n\n<p>\u201cCompare Amoxapine vs. Elavil.\u201d <em>Iodine.&nbsp;<\/em><\/p>\n\n\n\n<p><a href=\"https:\/\/www.iodine.com\/compare\/amoxapine-vs-elavil\" target=\"_blank\" rel=\"noopener\">https:\/\/www.iodine.com\/compare\/amoxapine-vs-elavil<\/a><\/p>\n\n\n\n<p>Mayo Clinic Staff. \u201cTricyclic Antidepressants and Tetracyclic Antidepressants.\u201d <em>Mayo Clinic.&nbsp;<\/em><\/p>\n\n\n\n<p><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/depression\/in-depth\/antidepressants\/art-20046983\" target=\"_blank\" rel=\"noopener\">https:\/\/www.mayoclinic.org\/diseases-conditions\/depression\/in-depth\/antidepressants\/art-20046983<\/a><\/p>\n\n\n\n<p>Craig Sawchuk. \u201cDepression (Major Depressive Disorder).\u201d <em>Mayo Clinic.&nbsp;<\/em><\/p>\n\n\n\n<p><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/depression\/symptoms-causes\/syc-20356007\" target=\"_blank\" rel=\"noopener\">https:\/\/www.mayoclinic.org\/diseases-conditions\/depression\/symptoms-causes\/syc-20356007<\/a><\/p>\n\n\n\n<p>\u201cSerotonin Syndrome.\u201d <em>Cleveland Clinic.&nbsp;<\/em><\/p>\n\n\n\n<p><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/17687-serotonin-syndrome\" target=\"_blank\" rel=\"noopener\">https:\/\/my.clevelandclinic.org\/health\/diseases\/17687-serotonin-syndrome<\/a><\/p>\n\n\n\n<p>Seth Gordon. \u201cAmitriptyline: Off-Label Uses For Certain Types Of Pain.\u201d <em>RO Health Guide.<\/em><\/p>\n\n\n\n<p><a href=\"https:\/\/ro.co\/health-guide\/amitriptyline-for-pain\/#wait-what-is-off-label-is-that-dangerous\" target=\"_blank\" rel=\"noopener\">https:\/\/ro.co\/health-guide\/amitriptyline-for-pain\/#wait-what-is-off-label-is-that-dangerous<\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Though amoxapine and amitriptyline have similar effects on the body and brain, one may work better for you depending on your symptoms, body chemistry, and contraindicated medications or conditions. The comparison guide below can help you decide which one may be right for you. <\/p>\n","protected":false},"author":29,"featured_media":6129,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18],"tags":[75],"temp_settings":[116],"_links":{"self":[{"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/posts\/6113"}],"collection":[{"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/comments?post=6113"}],"version-history":[{"count":9,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/posts\/6113\/revisions"}],"predecessor-version":[{"id":17195,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/posts\/6113\/revisions\/17195"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/media\/6129"}],"wp:attachment":[{"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/media?parent=6113"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/categories?post=6113"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/tags?post=6113"},{"taxonomy":"temp_settings","embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/temp_settings?post=6113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}