{"id":5285,"date":"2022-10-31T09:08:00","date_gmt":"2022-10-31T16:08:00","guid":{"rendered":"https:\/\/cms.helloklarity.com\/?p=5285"},"modified":"2024-02-01T13:17:40","modified_gmt":"2024-02-01T21:17:40","slug":"vyvanse-and-wellbutrin","status":"publish","type":"post","link":"https:\/\/cms.helloklarity.com\/post\/vyvanse-and-wellbutrin\/","title":{"rendered":"Vyvanse and Wellbutrin: Can You Take Them Together?"},"content":{"rendered":"\n<p>People with attention deficit hyperactivity disorder (ADHD) are almost three times more likely to develop depression than the general population. Treating both conditions is important, but are there effective treatment options that can simultaneously help treat <a href=\"https:\/\/www.klarityadhd.com\/adhd\/\" target=\"_blank\" rel=\"noopener\">ADHD<\/a> and <a href=\"https:\/\/www.klarityadhd.com\/depression\/\" target=\"_blank\" rel=\"noopener\">depression<\/a>?<\/p>\n\n\n\n<p>Vyvanse and Wellbutrin are two different medications that can work synergistically to treat symptoms of ADHD and other comorbid mood disorders like depression. If you have ADHD and experience depression, this combination of medications might be right for you.<\/p>\n\n\n\n<p>However, taking Vyvanse or Wellbutrin, either singly or together, is not recommended for everyone. In this post, Klarity discusses Vyvanse and Wellbutrin and how both can work together to help people with comorbid ADHD and depression symptoms. We\u2019ll also address situations where Vyvanse or Wellbutrin might not be right for you.&nbsp;<\/p>\n\n\n\n<p><em>Want to talk to a medical provider about how Vyvanse and Wellbutrin interact but don\u2019t have the time to wait weeks for an appointment?<\/em>&nbsp;<\/p>\n\n\n\n<p>Klarity makes it easy to book an appointment with a board-certified, fully licensed mental health provider who can help you find <a href=\"https:\/\/www.klarityadhd.com\/adhd\/\" target=\"_blank\" rel=\"noopener\">online ADHD treatment<\/a> and <a href=\"https:\/\/www.klarityadhd.com\/depression\/\" target=\"_blank\" rel=\"noopener\">online depression treatment<\/a>.<\/p>\n\n\n\n<p>Here\u2019s how it works\u2014<\/p>\n\n\n\n<p><a href=\"https:\/\/care.klarityadhd.com\/assessment\/get-started\" target=\"_blank\" rel=\"noopener\">Schedule an appointment<\/a> with an ADHD-trained mental health provider who can diagnose ADHD and depression and prescribe Vyvanse and Wellbutrin, if necessary, within <strong>48 hours<\/strong>.<em>&nbsp;<\/em><\/p>\n\n\n\n<p><em>This article discusses suicide, suicidal ideation, and self-harm. If you or someone you know is experiencing suicidal thoughts or is in crisis, contact the Suicide Prevention Lifeline immediately at 800-273-8255.<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What is Vyvanse?<\/strong><\/h2>\n\n\n\n<p>Vyvanse is a central nervous system stimulant. The main ingredient in Vyvanse is lisdexamfetamine dimesylate. Once it hits your body\u2019s GI tract, it is converted to an active ingredient\u2014dextroamphetamine, a type of amphetamine used to treat attention deficit hyperactivity disorder.<\/p>\n\n\n\n<p>As a stimulant medication, Vyvanse increases the amount of norepinephrine and dopamine in the brain. Norepinephrine is a neurotransmitter that stimulates the central nervous system, improving alertness, concentration, and cognition. Dopamine is a neurotransmitter whose function is crucial to the brain&#8217;s reward center. It is the \u201cfeel good\u201d neurotransmitter.<\/p>\n\n\n\n<p>As a result, Vyvanse produces feelings of euphoria and well-being in addition to helping improve concentration and attention span and reduce hyperactivity and impulsive behaviors. Because of Vyvanse\u2019s effect on impulsive behavior, it is FDA-approved to treat binge-eating disorder.<\/p>\n\n\n\n<p>However, as a stimulant medication, Vyvanse is a federally-controlled substance due to its addictive nature and risk of dependence, among other side effects. Sharing your prescription of Vyvanse or other medications of the same class with another person is illegal.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Forms and Dosages<\/strong><\/h3>\n\n\n\n<p>Vyvanse is available in oral capsules and chewable tablets. It is mostly prescribed in oral tablet form. Usually, patients start on a daily dose of 10mg by mouth and gradually increase the dosage if no interactions or reactions occur.<\/p>\n\n\n\n<p>Vyvanse oral capsules are available in:<\/p>\n\n\n\n<ul>\n<li>10 mg&nbsp;<\/li>\n\n\n\n<li>20 mg&nbsp;<\/li>\n\n\n\n<li>30 mg&nbsp;<\/li>\n\n\n\n<li>40 mg&nbsp;<\/li>\n\n\n\n<li>50 mg&nbsp;<\/li>\n\n\n\n<li>60 mg&nbsp;<\/li>\n\n\n\n<li>70 mg<\/li>\n<\/ul>\n\n\n\n<p>Vyvanse chewable tablets come in the following dosages:<\/p>\n\n\n\n<ul>\n<li>10 mg&nbsp;<\/li>\n\n\n\n<li>20 mg&nbsp;<\/li>\n\n\n\n<li>30 mg&nbsp;<\/li>\n\n\n\n<li>40 mg&nbsp;<\/li>\n\n\n\n<li>50 mg&nbsp;<\/li>\n\n\n\n<li>60 mg&nbsp;<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Conditions Treated<\/strong><\/h3>\n\n\n\n<p>Vyvanse treats symptoms of ADHD and moderate-to-mild binge eating disorder in patients older than six years of age. It is sometimes prescribed \u201coff-label\u201d for treatment-resistant depression.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Symptoms of ADHD Vyvanse Treats<\/strong><\/h4>\n\n\n\n<p>The core symptoms of attention deficit hyperactivity disorder are<strong> inattention, hyperactivity, and impulsivity<\/strong>. For adults with ADHD, hyperactivity symptoms are less severe than inattentive or impulsive symptoms.<\/p>\n\n\n\n<p><em>Inattentive Symptoms Include;<\/em><\/p>\n\n\n\n<ul>\n<li>Difficulty paying attention to tasks and conversations<\/li>\n\n\n\n<li>Difficulty organizing and prioritizing tasks and activities<\/li>\n\n\n\n<li>Difficulty following through\/completing directions, duties, responsibilities, and obligations<\/li>\n\n\n\n<li>Often loses important items like keys, wallets, phones, etc.<\/li>\n\n\n\n<li>Easily distracted, even by one\u2019s own thoughts<\/li>\n\n\n\n<li>Often misses appointments, fails to return calls or pay bills&nbsp;<\/li>\n<\/ul>\n\n\n\n<p><em>Impulsivity Symptoms Include:<\/em><\/p>\n\n\n\n<ul>\n<li>Has difficulty sitting still when doing so is expected<\/li>\n\n\n\n<li>Has difficulty being quiet when doing so is expected<\/li>\n\n\n\n<li>Fidgets often, tapping hands and feet<\/li>\n\n\n\n<li>Often squirms in seat and leaves seat when inappropriate<\/li>\n\n\n\n<li>Talks excessively and often interjects in conversations<\/li>\n\n\n\n<li>Interrupts and intrudes on others<\/li>\n<\/ul>\n\n\n\n<p>Because Vyvanse helps control symptoms of impulsivity, it is FDA-approved to treat binge-eating disorder (BED).&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Costs<\/strong><\/h3>\n\n\n\n<p>The cost of Vyvanse will depend on your dosage, pharmacy, and insurance. On average, a 30-day supply of 70 mg capsules without insurance or a product coupon is roughly $15 a pill, or $460.55 a month. There are no less-expensive, generic versions of Vyvanse. However, like with other medications, manufacturer&#8217;s coupons are available for people without insurance, reducing costs.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Side Effects and Drug Warnings<\/strong><\/h3>\n\n\n\n<p>Here are the common side effects drugs like Vyvanse have on the central nervous system.&nbsp;&nbsp;<\/p>\n\n\n\n<ul>\n<li>Insomnia (trouble falling and staying asleep)&nbsp;<\/li>\n\n\n\n<li>Decreased appetite&nbsp;<\/li>\n\n\n\n<li>Weight loss<\/li>\n\n\n\n<li>Abdominal (belly) pain&nbsp;<\/li>\n\n\n\n<li>Constipation<\/li>\n\n\n\n<li>Headache&nbsp;<\/li>\n\n\n\n<li>Nausea and vomiting&nbsp;<\/li>\n\n\n\n<li>Irritability&nbsp;<\/li>\n\n\n\n<li>Anxiety<\/li>\n\n\n\n<li>Crashing (some patients might experience increased tiredness and irritability as the medication wears off)<\/li>\n<\/ul>\n\n\n\n<p>Taking Vyvanse comes with the risk of more serious side effects, which are less common. These include:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Cardiovascular Problems<\/strong><\/h4>\n\n\n\n<ul>\n<li><strong>increased heartbeat<\/strong><\/li>\n\n\n\n<li>increased blood pressure<\/li>\n\n\n\n<li>heart attack<\/li>\n\n\n\n<li>chest pain (angina)&nbsp;<\/li>\n\n\n\n<li>sudden weakness\/numbness in the arm&nbsp;<\/li>\n\n\n\n<li>chest tightness with pain radiating to the neck, jaw, and throat&nbsp;<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Worsening Mental Health Symptoms<\/strong><\/h4>\n\n\n\n<ul>\n<li>Developing or worsening psychotic symptoms, including visual and auditory hallucinations and delusions<\/li>\n\n\n\n<li>Developing or worsening bipolar symptoms<\/li>\n\n\n\n<li>Developing or worsening manic symptoms<\/li>\n\n\n\n<li>Developing or worsening negative thought patterns and behavior<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Circulatory Symptoms&nbsp;<\/strong><\/h4>\n\n\n\n<ul>\n<li>\u201cRaynaud&#8217;s syndrome\u201d (problems with blood circulation in your fingers and toes)<\/li>\n<\/ul>\n\n\n\n<ul>\n<li>Due to lack of circulation, patients will notice their fingers look pale with blue, purple, red, or white discoloration.<\/li>\n\n\n\n<li>Fingers and toes might feel numb and cold&nbsp;<\/li>\n\n\n\n<li>Unexplained injuries, bruises, and cuts to fingers and toes<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Serotonin Syndrome<\/strong><\/h4>\n\n\n\n<p>Serotonin syndrome is a toxic build-up of serotonin that can be fatal. It occurs most often when starting a new medication that elevates serotonin levels or as a drug interaction between two medications that boost serotonin levels.<\/p>\n\n\n\n<p>This condition occurs hours after taking a new medication or increasing the dose of your current medication. Symptoms include:&nbsp;<\/p>\n\n\n\n<ul>\n<li>Seizures&nbsp;<\/li>\n\n\n\n<li>Muscle twitching and tremors<\/li>\n\n\n\n<li>Stiff muscles<\/li>\n\n\n\n<li>Fast heartbeat&nbsp;<\/li>\n\n\n\n<li>Loss of coordination<\/li>\n\n\n\n<li>Diarrhea&nbsp;<\/li>\n\n\n\n<li>Flushing (warmth, redness, and swelling of the face)<\/li>\n\n\n\n<li>Confusion&nbsp;<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Warnings and Drug Interactions<\/strong><\/h3>\n\n\n\n<p>Vyvanse is classified as a Schedule II drug under the Controlled Substances Act due to its stimulant properties, potential for misuse, and very high risk for dependency. This is because it belongs to the amphetamine class of medications. Long-term use, misuse, or high dosage may increase this risk, so it\u2019s crucial to take Vyvanse as prescribed and under close medical supervision.&nbsp;<\/p>\n\n\n\n<p>Additionally, if Vyvanse is discontinued suddenly, withdrawal symptoms can occur. Symptoms may vary in severity depending on the dosage and duration of use. The best way to stop taking Vyvanse is under the guidance of a healthcare provider.&nbsp;<\/p>\n\n\n\n<p>Common withdrawal symptoms include:<\/p>\n\n\n\n<ul>\n<li>Fatigue&nbsp;<\/li>\n\n\n\n<li>Depression or anxiety&nbsp;<\/li>\n\n\n\n<li>Irritability&nbsp;<\/li>\n\n\n\n<li>Difficulty sleeping&nbsp;<\/li>\n\n\n\n<li>Increased appetite&nbsp;<\/li>\n\n\n\n<li>Headaches<\/li>\n\n\n\n<li>Difficulty concentrating&nbsp;<\/li>\n\n\n\n<li>Flu-like symptoms such as muscle aches and sweating<\/li>\n<\/ul>\n\n\n\n<p>Other medications frequently used to treat ADHD are also classified as Schedule II stimulants. The most frequently prescribed medications include:<\/p>\n\n\n\n<ul>\n<li>Methylphenidate (Ritalin, Concerta): Stimulant medications chemically different from amphetamines but have similar effects.<\/li>\n\n\n\n<li>Dextroamphetamine (<a href=\"https:\/\/www.klarityadhd.com\/post\/dexedrine-vs-adderall\/\" data-type=\"link\" data-id=\"https:\/\/www.klarityadhd.com\/post\/dexedrine-vs-adderall\/\" target=\"_blank\" rel=\"noopener\">Dexedrine<\/a>): An amphetamine medication used for ADHD and narcolepsy.<\/li>\n\n\n\n<li>Lisdexamfetamine (Vyvanse): A prodrug that remains inactive until metabolized in the body, prescribed for ADHD and binge eating disorder.<\/li>\n\n\n\n<li>Methamphetamine (Desoxyn): A potent central nervous system stimulant used in rare instances to treat ADHD and obesity.<\/li>\n<\/ul>\n\n\n\n<p>It&#8217;s important to note that Vyvanse should always be taken under the guidance and supervision of a healthcare professional. Understanding the potential risks and side effects associated with this and similar medications can help individuals make informed decisions about their treatment options.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Serotonin Syndrome<\/strong><\/h4>\n\n\n\n<p>Serotonin syndrome is a rare but potentially fatal condition that occurs when there is too much serotonin in your body. Usually, serotonin toxicity occurs when patients increase their dose of medication or start a new medication that affects serotonin levels.&nbsp;<\/p>\n\n\n\n<p>Serotonin syndrome usually occurs within a few hours of taking a higher dose of medication or starting other medications that elevate serotonin. Symptoms of serotonin include:<\/p>\n\n\n\n<ul>\n<li>Insomnia<\/li>\n\n\n\n<li>Confusion<\/li>\n\n\n\n<li>Agitation<\/li>\n\n\n\n<li>Restlessness<\/li>\n\n\n\n<li>Rapid heart rate and high blood pressure<\/li>\n\n\n\n<li>High blood pressure<\/li>\n\n\n\n<li>Muscle rigidity<\/li>\n\n\n\n<li>Dilated pupils<\/li>\n\n\n\n<li>Loss of muscle coordination or twitching muscles<\/li>\n<\/ul>\n\n\n\n<p>To prevent serotonin syndrome, patients prescribed Vyvanse should stop taking MAO inhibitors 14 days before starting stimulant medications like Vyvanse.&nbsp;<\/p>\n\n\n\n<p>Common MAO inhibitors are:<\/p>\n\n\n\n<ul>\n<li>Isocarboxazid&nbsp;<\/li>\n\n\n\n<li>Linezolid<\/li>\n\n\n\n<li>Methylene blue injection&nbsp;<\/li>\n\n\n\n<li>Phenelzine&nbsp;<\/li>\n\n\n\n<li>Rasagiline&nbsp;<\/li>\n\n\n\n<li>Selegiline&nbsp;<\/li>\n\n\n\n<li>Tranylcypromine&nbsp;<\/li>\n<\/ul>\n\n\n\n<p>Always talk to your medical provider when stopping or starting other medications to avoid drug interactions.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Vyvanse and Alcohol<\/strong><\/h4>\n\n\n\n<p>Though there are no specific studies on Vyvanse and alcohol\u2019s combined use, there have been studies on amphetamines, a similar drug, and alcohol. Mixing amphetamines and alcohol raises heart rate and blood pressure.<\/p>\n\n\n\n<p>CNS stimulants can mask the effects of alcohol intoxication, which leads to people drinking more than they should\u2014taking Vyvanse while drinking alcohol can lead to alcohol poisoning and injuries associated with drunkenness, like falling.<\/p>\n\n\n\t\t<div data-elementor-type=\"page\" data-elementor-id=\"15401\" class=\"elementor elementor-15401\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c521b1f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c521b1f\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1e5f769\" data-id=\"1e5f769\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-8537e6b elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8537e6b\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-f020c0d\" data-id=\"f020c0d\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2478e2a elementor-widget__width-auto elementor-widget elementor-widget-heading\" data-id=\"2478e2a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.19.0 - 07-02-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-large\">Licensed providers on Klarity provide personalized treatment. \nFind a provider that matches your needs and preferences.<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-87df69e elementor-widget elementor-widget-spacer\" data-id=\"87df69e\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.19.0 - 07-02-2024 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container{height:100%;width:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty,.e-con>.elementor-widget-spacer.elementor-widget-empty{position:relative;min-height:22px;min-width:22px}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon,.e-con>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon{position:absolute;top:0;bottom:0;left:0;right:0;margin:auto;padding:0;width:22px;height:22px}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-76f1234 elementor-widget-tablet__width-inherit elementor-tablet-align-center elementor-align-center elementor-widget__width-auto elementor-widget elementor-widget-button\" data-id=\"76f1234\" data-element_type=\"widget\" data-settings=\"{&quot;sticky&quot;:&quot;top&quot;,&quot;sticky_on&quot;:[&quot;mobile&quot;],&quot;sticky_offset_mobile&quot;:0,&quot;sticky_effects_offset_mobile&quot;:0,&quot;sticky_offset&quot;:0,&quot;sticky_effects_offset&quot;:0}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-md\" href=\"https:\/\/care.helloklarity.com\/assessment\/get-started?utm_source=blog&#038;utm_medium=cta&#038;utm_campaign=blue\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">Find a provider<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What is Wellbutrin?<\/strong><\/h2>\n\n\n\n<p>Wellbutrin (bupropion) is a unique antidepressant medication. It is an NDRI or norepinephrine-dopamine reuptake inhibitor. Like other antidepressant medication, this medication is FDA-approved to treat major depressive disorder (MDD) and seasonal affective disorder (SAD) and is prescribed to help with smoking cessation and weight loss.<\/p>\n\n\n\n<p>Like Vyvanse, taking Wellbutrin elevates levels of dopamine and norepinephrine. Dopamine is responsible for feelings of well-being and is a vital part of the brain&#8217;s reward center. Norepinephrine excites the central nervous system and affects attention, concentration, and cognition.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Forms and Dosages<\/strong><\/h3>\n\n\n\n<p>Wellbutrin is available in two types of modified-release oral tablets\u2014controlled release (Wellbutrin XL) or sustained release (Wellbutrin SR). Both Wellbutrin XL and Wellbutrin SR are considered \u201cextended release.\u201d Both are intended as a daily dose.<\/p>\n\n\n\n<ul>\n<li><strong>Controlled Release<\/strong>: The medication is slowly released constantly over time.<\/li>\n\n\n\n<li><strong>Sustained Release<\/strong>: The medication is slowly released over time, but not constantly.&nbsp;<\/li>\n<\/ul>\n\n\n\n<p>When you speak with your Klarity medical provider, they\u2019ll help determine which form and dosage are best for you.&nbsp;<\/p>\n\n\n\n<p>Oral tablet, sustained release (Wellbutrin SR):<\/p>\n\n\n\n<ul>\n<li>100 mg&nbsp;<\/li>\n\n\n\n<li>150 mg&nbsp;<\/li>\n\n\n\n<li>200 mg<\/li>\n<\/ul>\n\n\n\n<p>Oral tablet, controlled-release (Wellbutrin XL):<\/p>\n\n\n\n<ul>\n<li>150 mg<\/li>\n\n\n\n<li>300 mg<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Conditions Treated<\/strong><\/h3>\n\n\n\n<p>Wellbutrin, Wellbutrin XL, and Wellbutrin SR are primarily prescribed to treat depression symptoms. In addition to treating depressive disorders, Wellbutrin is FDA-approved as a smoking cessation aid.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Depression Symptoms Wellbutrin Can Treat<\/strong><\/h4>\n\n\n\n<ul>\n<li>Sadness<\/li>\n\n\n\n<li>Feeling empty and hopeless<\/li>\n\n\n\n<li>Outbursts of anger, frustration, and irritability<\/li>\n\n\n\n<li>Reduced or lack of interest in hobbies and activities that used to bring joy<\/li>\n\n\n\n<li>Sleep disturbances: insomnia, oversleeping sleeping<\/li>\n\n\n\n<li>Feeling tired, lethargic, and \u201cheavy\u201d or weighed down<\/li>\n\n\n\n<li>Changes in appetite: eating too much or too little<\/li>\n\n\n\n<li>Increased anxiety, restlessness, and agitation<\/li>\n\n\n\n<li>Speaking and moving as if in slow motion<\/li>\n\n\n\n<li>Difficulty thinking, concentrating, remembering, and making decisions<\/li>\n\n\n\n<li>Unexplained pains and aches<\/li>\n\n\n\n<li>Feelings of worthlessness, ruminating on past mistakes and failures<\/li>\n\n\n\n<li>Unnatural guilt or shame<\/li>\n\n\n\n<li>Thoughts of death, suicide, and feeling like you\u2019d be better off if not alive.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Costs<\/strong><\/h3>\n\n\n\n<p>The cost of Wellbutrin XL and Wellbutrin SR will depend on your dosage, pharmacy, and insurance. A 30-day supply of Wellbutrin\u201430 tablets\u2014costs about $86.62, or $2.89 per pill. Health insurance will drastically reduce the cost of Wellbutrin. If you do not have health insurance, there are coupons and copay assistance programs available to reduce the costs of Wellbutrin.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Side Effects<\/strong><\/h3>\n\n\n\n<p>All antidepressants carry some risk of side effects. Common <a href=\"https:\/\/www.helloklarity.com\/post\/wellbutrin-side-effects\/\">side effects of Wellbutrin<\/a> XL and SR include:<\/p>\n\n\n\n<ul>\n<li>Anxiety<\/li>\n\n\n\n<li>Abnormal or unusual dreams<\/li>\n\n\n\n<li>Tachycardia (fast heartbeat)<\/li>\n\n\n\n<li>Hyperventilation&nbsp;<\/li>\n\n\n\n<li>Excessive sweating&nbsp;<\/li>\n\n\n\n<li>Blurred vision&nbsp;<\/li>\n\n\n\n<li>Irritability<\/li>\n\n\n\n<li>Migraine<\/li>\n\n\n\n<li>Dry mouth<\/li>\n\n\n\n<li>Constipation<\/li>\n\n\n\n<li>Insomnia (trouble sleeping)&nbsp;<\/li>\n\n\n\n<li>Skin rash&nbsp;<\/li>\n\n\n\n<li>Confusion&nbsp;<\/li>\n\n\n\n<li>Dizziness and fainting<\/li>\n\n\n\n<li>Nausea and vomiting<\/li>\n\n\n\n<li>Tremors<\/li>\n\n\n\n<li>Excessive energy (excessive talking, hyperactivity, and fidgeting)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.helloklarity.com\/post\/does-wellbutrin-cause-hair-loss\/\">Hair loss<\/a><\/li>\n<\/ul>\n\n\n\n<p>These side effects are often minor and disappear after a few days or weeks. However, if the above side effects persist over a few weeks, worsen, and interfere with your daily functioning, then talk to your medical provider about stopping or reducing the dosage.<\/p>\n\n\n\n<p>Wellbutrin XL and SR can cause more serious side effects in a small percentage of Wellbutrin users. If prescribed Wellbutrin, monitor for the following side effects:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Mental Health Side Effects:<\/strong><\/h4>\n\n\n\n<ul>\n<li>Panic attacks<\/li>\n\n\n\n<li>Changes in mood<\/li>\n\n\n\n<li>Increased impulsiveness<\/li>\n\n\n\n<li>Increased depression<\/li>\n\n\n\n<li>Increased anxiety&nbsp;<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Other Serious Side Effects:<\/strong><\/h4>\n\n\n\n<ul>\n<li>Hypertension<\/li>\n\n\n\n<li>Vision Issues<\/li>\n\n\n\n<li>Seizures&nbsp;<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Warnings and Drug Interactions<\/strong><\/h3>\n\n\n\n<p>People prone to seizures, whether due to medication, a seizure disorder, or injury, must disclose this to their medical providers before taking Wellbutrin. 0.1% &#8211; 0.4% of Wellbutrin users experience seizures or an increased risk of having a seizure. This is especially true with alcohol use.<\/p>\n\n\n\n<p>Unlike SSRIs, Wellbutrin does not have widely reported sexual side effects.&nbsp;<\/p>\n\n\n\n<p>Wellbutrin can affect your weight and appetite, causing weight loss or weight gain. Be sure to disclose any history of eating disorders with your medical provider before taking Wellbutrin.<\/p>\n\n\n\n<p>Wellbutrin might not be right for people with liver and kidney issues due to the increased strain on these organs when metabolizing Wellbutrin. People with diabetes and bipolar mood disorder should also not take Wellbutrin.<\/p>\n\n\n\n<p>Also, Wellbutrin should not be prescribed to those with bipolar disorder or schizophrenia, and it has a small risk of causing psychosis in some patients.<\/p>\n\n\n\n<p><strong>Serotonin Syndrome<\/strong>:<\/p>\n\n\n\n<p>Though Wellbutrin primarily prevents the reuptake of norepinephrine and dopamine, which elevates the base levels of the two neurotransmitters, it also boosts serotonin to a lesser extent.<\/p>\n\n\n\n<p>Because of this, Wellbutrin should not be taken with other medications that increase serotonin levels, including SSRIs and MAOIs.<\/p>\n\n\n\n<p>Common MAOIs include:<\/p>\n\n\n\n<ul>\n<li>Isocarboxazid&nbsp;<\/li>\n\n\n\n<li>Linezolid<\/li>\n\n\n\n<li>Methylene blue injection&nbsp;<\/li>\n\n\n\n<li>Phenelzine&nbsp;<\/li>\n\n\n\n<li>Rasagiline&nbsp;<\/li>\n\n\n\n<li>Selegiline&nbsp;<\/li>\n\n\n\n<li>Tranylcypromine&nbsp;<\/li>\n<\/ul>\n\n\n\n<p>Common SSRIs include:<\/p>\n\n\n\n<ul>\n<li>Fluoxetine (Prozac)<\/li>\n\n\n\n<li>Paroxetine (Paxil, Pexeva)<\/li>\n\n\n\n<li>Sertraline (Zoloft)<\/li>\n\n\n\n<li>Citalopram (<a href=\"https:\/\/www.klarityadhd.com\/post\/prozac-vs-celexa\/\" data-type=\"link\" data-id=\"https:\/\/www.klarityadhd.com\/post\/prozac-vs-celexa\/\" target=\"_blank\" rel=\"noopener\">Celexa<\/a>)<\/li>\n\n\n\n<li>Escitalopram (Lexapro)<\/li>\n<\/ul>\n\n\n\n<p><strong>Black Box Warning:<\/strong><\/p>\n\n\n\n<p>All antidepressants come with a black box warning from the FDA. In placebo-controlled trials of antidepressants, researchers saw an increase in suicidal thoughts and ideation among children and adolescents taking antidepressants compared to the placebo group.<\/p>\n\n\n\n<p>These findings have not been replicated in adults. However, it&#8217;s important for people taking antidepressants to monitor for sudden mood, thoughts, and behavior changes. If these are experienced, contact your healthcare provider immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>How Do Vyvanse and Wellbutrin Work Together?<\/strong><\/h2>\n\n\n\n<p>Though they use different mechanisms, Vyvanse and Wellbutrin increase the available amounts of norepinephrine and dopamine in the brain. Because of this, Vyvanse and Wellbutrin have a synergistic effect when used to treat ADHD and depression.&nbsp;<\/p>\n\n\n\n<p>Attention deficit hyperactivity disorder is often comorbid with other mental health conditions, including many varieties of depression, like seasonal affective disorder. These medications might be suitable for people with ADHD who have comorbid depression. However, taking the two medicines together increases the risk of certain side effects, such as seizures or negative drug interactions.<\/p>\n\n\n\n<p>Here&#8217;s a breakdown of the potential benefits and drawbacks:<\/p>\n\n\n\n<p><strong>Benefits<\/strong>:<\/p>\n\n\n\n<ul>\n<li>Vyvanse and Wellbutrin may be prescribed together to help treat ADHD and treat depression in people who have both conditions.<\/li>\n\n\n\n<li>Vyvanse and Wellbutrin may have complementary effects, as Vyvanse can help improve focus and attention, while Wellbutrin can help improve mood and reduce symptoms of depression.<\/li>\n<\/ul>\n\n\n\n<p><strong>Risks<\/strong>:<\/p>\n\n\n\n<ul>\n<li>Combining Wellbutrin with Vyvanse may increase the risk of side effects, such as high blood pressure, heart palpitations, and insomnia.<\/li>\n\n\n\n<li>Both medications can increase the risk of seizures, and combining them may further increase this risk.<\/li>\n\n\n\n<li>Taking Vyvanse and Wellbutrin together may increase the risk of drug dependence and abuse.<\/li>\n\n\n\n<li>Some people may experience an increased risk of suicidal thoughts or behaviors when taking Wellbutrin.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Klarity Helps You Discover The Right ADHD Medication<\/strong><\/h2>\n\n\n\n<p>Klarity has helped more than 30,000 people find diagnoses and treatment for various mental health issues\u2014including ADHD and depression. Our novel telehealth service makes finding online ADHD and depression treatment affordable, fast, and convenient.&nbsp;<\/p>\n\n\n\n<p><em>So, if you are curious about trying Vyvanse and Wellbutrin together to manage ADHD and depression symptoms, book an appointment on Klarity. Here\u2019s why\u2014<\/em><\/p>\n\n\n\n<p><strong>Klarity is Fast: <\/strong>We will get you a virtual<a href=\"https:\/\/www.klarityadhd.com\/treatment\/\" target=\"_blank\" rel=\"noopener\"> appointment with a licensed healthcare provider<\/a> in your state within 48 hours.<\/p>\n\n\n\n<p><strong>Klarity is Convenient:<\/strong> Meet with us anywhere you have cell service or wifi\u2014we put the doctor\u2019s office in your pocket.<\/p>\n\n\n\n<p><a href=\"https:\/\/care.klarityadhd.com\/assessment\/get-started\" target=\"_blank\" rel=\"noopener\">Schedule an appointment<\/a> today to get started.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-layout-1 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p>Sources:&nbsp;<\/p>\n\n\n\n<p>Carl Sherman. \u201cIs It ADHD, Depression, or Both?\u201d <em>ADDitude<\/em>. <a href=\"https:\/\/www.additudemag.com\/adhd-and-depression-symptoms-treatment\/\" target=\"_blank\" rel=\"noopener\">https:\/\/www.additudemag.com\/adhd-and-depression-symptoms-treatment\/<\/a><\/p>\n\n\n\n<p>\u201cDrug interactions between bupropion\/naltrexone and Vyvanse.\u201d <em>Drugs.<\/em> <a href=\"https:\/\/www.drugs.com\/drug-interactions\/bupropion-naltrexone-with-vyvanse-3559-0-1475-2533.html\" target=\"_blank\" rel=\"noopener\">https:\/\/www.drugs.com\/drug-interactions\/bupropion-naltrexone-with-vyvanse-3559-0-1475-2533.html<\/a><\/p>\n\n\n\n<p>\u201cBupropion (Oral Route) &#8211; Mayo Clinic\u201d&nbsp;<\/p>\n\n\n\n<p><a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/bupropion-oral-route\/precautions\/drg-20062478\" target=\"_blank\" rel=\"noopener\"><em>https:\/\/www.mayoclinic.org<\/em><\/a>,<a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/bupropion-oral-route\/precautions\/drg-20062478\" target=\"_blank\" rel=\"noopener\">https:\/\/www.mayoclinic.org\/drugs-supplements\/bupropion-oral-route\/precautions\/drg-20062478<\/a>&nbsp;<\/p>\n\n\n\n<p>Jacqueline Sinfield. \u201cUsing Wellbutrin for ADHD.\u201d <em>Very Well Mind<\/em>. <a href=\"https:\/\/www.verywellmind.com\/using-wellbutrin-for-adhd-4137671\" target=\"_blank\" rel=\"noopener\">https:\/\/www.verywellmind.com\/using-wellbutrin-for-adhd-4137671<\/a><\/p>\n\n\n\n<p>Janice Rodden. \u201cWellbutrin.\u201d <em>ADDitude<\/em>. <a href=\"https:\/\/www.additudemag.com\/medication\/wellbutrin\/#:~:text=When%20prescribed%20for%20ADHD%20treatment,like%20Vyvanse%20or%20Adderall%20XR\" target=\"_blank\" rel=\"noopener\">https:\/\/www.additudemag.com\/medication\/wellbutrin\/#:~:text=When%20prescribed%20for%20ADHD%20treatment,like%20Vyvanse%20or%20Adderall%20XR<\/a>.<\/p>\n\n\n\n<p>Renato P. Munhoz. \u201cSerotonin syndrome induced by a combination of bupropion and SSRIs.\u201d <em>National Library of Medicine. <\/em><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15602102\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/15602102\/<\/a><\/p>\n\n\n\n<p>\u201cVyvanse: Dosage, side effects, alternatives and more &#8211; Medical News Today.\u201d&nbsp;<\/p>\n\n\n\n<p><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/vyvanse#side-effects\" target=\"_blank\" rel=\"noopener\"><em>https:\/\/www.medicalnewstoday.com<\/em>,https:\/\/www.medicalnewstoday.com\/articles\/vyvanse#side-effects<\/a>&nbsp;<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>People with attention deficit hyperactivity disorder (ADHD) are almost three times more likely to develop depression than the general population. Treating both conditions is important, but are there effective treatment options that can simultaneously help treat ADHD and depression? Vyvanse and Wellbutrin are two different medications that can work synergistically to treat symptoms of ADHD [&hellip;]<\/p>\n","protected":false},"author":29,"featured_media":5286,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16,18],"tags":[73,75],"temp_settings":[116],"_links":{"self":[{"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/posts\/5285"}],"collection":[{"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/comments?post=5285"}],"version-history":[{"count":23,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/posts\/5285\/revisions"}],"predecessor-version":[{"id":17999,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/posts\/5285\/revisions\/17999"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/media\/5286"}],"wp:attachment":[{"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/media?parent=5285"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/categories?post=5285"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/tags?post=5285"},{"taxonomy":"temp_settings","embeddable":true,"href":"https:\/\/cms.helloklarity.com\/wp-json\/wp\/v2\/temp_settings?post=5285"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}