Which medication is the best for your ADHD? The answer depends on a number of factors, from what kind of ADHD you have to your medical history. This is especially true when it comes to trying to choose between similar ADHD medications like Mydayis and Adderall.
Both of these drugs are central nervous system stimulants with nearly identical ingredients. Choosing one over the other is a matter of understanding the subtle differences in how they affect the body and mind, from side effects to interactions.
The comparison guide below provides comprehensive information on each medication and explains their similarities and differences, cost, and contraindicated conditions. This will help you and your healthcare provider choose the best medication to manage your ADHD.
It’s difficult to determine which medication is the best choice for you, which is why Klarity connects patients with healthcare providers for easy and accessible online ADHD treatment. Schedule an online visit with a licensed, certified mental health provider in your state who can help you start relieving your ADHD symptoms in as little as 48 hours.
| Mydayis | Adderall | |
|---|---|---|
| Drug Class | Schedule II stimulant | Schedule II stimulant |
| Brand / Generic Status | Brand name for dextroamphetamine/ amphetamine |
Brand name for amphetamine salts |
| Form(s) of the Drug | Capsules | Immediate release tablets |
| Standard Dosage | 12.5mg, 25mg, 37.5mg, and 50 mg extended-release capsules | 5mg to 30mg tablets |
| Conditions Treated | FDA-approved uses: • ADHD Off-label uses: • Various sleeping disorders |
FDA-approved uses: • ADHD • Narcolepsy Off-label uses: • Depression • Anxiety • Bipolar disorder |
| Cost | Brand-name Mydayis: • $1000 for 100 capsules Generic form (only available as a brand name) |
Brand-name Adderall: • $8 per 5mg tablet • $237 for a 30-day supply Generic form (amphetamine salts): • $13 for 30 days of 5mg tablets • $85 for 30 extended-release pills |
| Side-Effects | Common side effects: • Insomnia • Decreased appetite • Weight loss • Dry mouth • Elevated heart rate • Anxiety Serious side effects: • Seizures • Exacerbated heart problems • Increased mental problems |
Common side-effects: • Decreased appetite • Weight loss • Dry mouth • Nausea • Headache • Fever • Trouble sleeping Serious side-effects: • Signs of blood flow problems • Behavior changes • Uncontrolled movements • Shortness of breath • Irregular heartbeat • Seizures • Trouble speaking |
| Warnings For Use | Contraindicated for: • Kidney failure • MAOI use • Pregnancy or breastfeeding • Antidepressants |
Drug interactions: • SSRIs and SNRIs • Blood pressure medication • Acid reflux medication • Blood thinners • Cold or allergy medication • Opioid-based medications • Seizure medication |
What is Mydayis?
Mydayis is an amphetamine-based ADHD medication that works by targeting neurotransmitters in the brain that control things like hyperactivity, impulsivity, and issues with focus. This medication, like Adderall, is a central nervous system stimulant.
The difference is that Mydayis is a single-entity amphetamine product designed to last up to 16 hours in an extended-release capsule, while Adderall comes in both an immediate-release tablet designed to last 4-6 hours and an extended-release tablet (Adderall XR) that typically lasts over a 12-hour period.
Forms and Dosages
Mydayis capsules begin at a dosage of 12.5 mg. Dosages can be increased to 25 mg, 37.5 mg, and 50 mg doses depending on the patient’s needs. Mydayis’s capsules are designed to disburse a steady stream of medication into the bloodstream over a 16-hour period.
Conditions Treated
Mydayis is primarily used to treat ADHD (attention-deficit hyperactivity disorder), but it can be used off-label to treat narcolepsy and other sleep disorders.
Costs
Mydayis comes in generic and branded forms. Out-of-pocket cost (not on an insurance plan) associated with this ADHD medication is approximately $450 to $500 for a one month (30 day) supply. You can expect the price for a generic supply of the medication under a health insurance plan to be drastically cheaper, as both SpecGX and Sun received FDA-approval as generic forms of Mydayis in August and September 2023.
For accurate pricing under your health insurance, contact your provider’s pharmacy department.
Side Effects
Side effects of Mydayis treatment in adults include but are not limited to:
- Insomnia
- Decreased appetite
- Weight loss
- Dry mouth
- Elevated heart rate
- Anxiety
The more severe but rarer side effects of Mydayis include:
- Seizures
- Exacerbated heart or mental problems
For more information on side effects, warnings, and drug interactions, speak with a healthcare provider who can explain the benefits and drawbacks of using an ADHD stimulant medication like Mydayis. If you experience any serious or life-threatening side effects, seek emergency medical care immediately.
Warnings and Drug Interactions
When considering Mydayis for ADHD treatment, it’s important to be aware of potential warnings and drug interactions. Mydayis, an extended-release medication, can significantly impact the cardiovascular system. Monitoring blood pressure and heart rate is crucial, especially for patients with pre-existing heart conditions. Psychological side effects, including increased anxiety, mood swings, and in some cases, psychotic symptoms, may also occur.
Mydayis can interact with several types of medications. It’s vital to inform your healthcare provider of all drugs you’re taking. Key interactions include:
- Antidepressants: Besides MAO inhibitors (e.g., Isocarboxazid, Selegiline), SSRIs such as Sertraline and Citalopram, and SNRIs like Venlafaxine, can also interact with Mydayis.
- Blood Pressure Medications: This includes calcium channel blockers like Amlodipine and diuretics such as Hydrochlorothiazide, which may have reduced efficacy with Mydayis.
- Acidifying Agents: Examples are citric acid (found in citrus fruits) and cranberry juice, which can decrease the absorption of Mydayis.
- Alkalinizing Agents: Agents like potassium citrate and antacids such as calcium carbonate can increase the absorption of Mydayis, possibly leading to higher blood levels and effects.
Always consult with a healthcare professional before starting or changing your Mydayis regimen, particularly if you are taking other medications.
What is Adderall?
Adderall is a central nervous system stimulant composed of two medications: amphetamine and dextroamphetamine. These ingredients work by targeting neurotransmitters in the brain, like dopamine and serotonin. By altering the behavior of certain neurotransmitters, Adderall effectively manages ADHD symptoms like hyperactivity, impulsivity, and lack of attention and focus.
Adderall comes in 2 forms, Adderall IR and Adderall XR. Adderall IR is an immediate-release medication, but it only treats symptoms for about 5-8 hours. Adderall XR, on the other hand, is an extended-release medication that helps alleviate symptoms of ADHD for 10-12 hours.
Forms and Dosages
Adderall comes in 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg, 20 mg, and 30 mg tablets. Adderall is in generic form and can be in either an immediate-release tablet (IR) or extended-release (XR) formula that lasts up to 12 hours per capsule.
Adderall IR is taken 1-2 times per day, depending on a patient’s needs. The last dose of the day should not be taken after 12 PM to avoid losing sleep or experiencing restlessness.
Conditions Treated
Adderall is approved by the Food and Drug Administration (FDA) to combat ADHD (attention-deficit hyperactivity disorder) and narcolepsy.
Costs
Adderall is in a generic form, drastically reducing the cost of the medication when it is off-brand. Without insurance, you can expect to pay around $8 daily for Adderall. With health insurance, you are likely to pay no more than $30 for a one-month supply. For accurate pricing information, contact your healthcare provider’s pharmacy department and ask for your insurance tier’s specific pricing.
Side Effects
Most stimulants carry a risk and should be avoided for those suffering from anxiety, heart issues, and circulation issues. The following are potential side effects of Adderall treatment:
- Irregular heartbeat
- Elevated heart rate
- Increased blood pressure
- Restlessness
- Dry mouth
- Diarrhea, constipation, nausea
- Headache
- Weight loss
- Mood changes
- Anxiety
- Dizziness
More severe but less common Adderall side effects include:
- Seizures
- Eyesight instability
- Urinary tract infection
- Nausea
- Fever
- Stroke
- Heart attack
Warnings and Drug Interactions
When considering Adderall for ADHD treatment, it’s crucial to be aware of potential warnings and drug interactions. Adderall can have significant effects on the cardiovascular system, making it essential to monitor blood pressure and heart rate, especially in patients with pre-existing heart conditions. There’s also a risk of developing psychological side effects, such as increased anxiety, mood swings, and in rare cases, psychotic symptoms.
Adderall can interact with several types of medications, so it’s important to inform your healthcare provider of all drugs you’re taking. Some notable interactions include:
- Antidepressants: In addition to MAO inhibitors like Phenelzine and Tranylcypromine, SSRIs (e.g., Sertraline, Fluoxetine) and SNRIs (e.g., Venlafaxine, Duloxetine) may also interact with Adderall.
- Blood pressure medications: This includes beta-blockers like Atenolol and Metoprolol, as well as ACE inhibitors such as Lisinopril and Enalapril, which may have reduced efficacy.
- Acidifying agents: Examples include vitamin C supplements and citric acid (found in citrus fruits), which can decrease Adderall absorption.
- Alkalinizing agents: Baking soda (sodium bicarbonate) and antacids like omeprazole or esomeprazole can increase Adderall absorption, potentially leading to higher blood levels and increased effects or side effects.
Always consult with a healthcare professional before starting or stopping Adderall, especially if you’re taking other prescription medications.
Licensed providers on Klarity provide personalized treatment. Find a provider that matches your needs and preferences.
Which Will Better Treat Your ADHD?
Mydayis and Adderall XR are both extended-release medications containing active ingredients like amphetamine sulfate to help treat symptoms of anxiety. Adderall is also available in an immediate-release version, and a provider can give you more information about the benefits of all three.
Mydayis is the first mixed amphetamine salts formula that can improve ADHD symptoms for as long as 16 hours with only one daily dose. However, both medications have similar benefits for those struggling with ADHD.
Both Adderall and Mydayis are schedule II drugs, meaning they are the stimulants with the highest risk of abuse and dependency. It’s important to note that Adderall and Mydayis should not be prescribed to those with a history of substance abuse, as there are additional options to treat ADHD that are less or non-addictive. A provider will speak to you about the pros and cons of each medication relative to your ADHD, and can help you determine which medication is the most suitable for you.
Find the Right ADHD Medication with Klarity
If you are struggling with symptoms of ADHD, FDA-approved prescription drugs like Adderall and Mydayis can be an effective treatment option.
The certified and licensed medical providers on Klarity will help you find the right ADHD medication within just 48 hours. Klarity has helped over 30,000 Americans find convenient online treatment for a variety of mental health conditions.
Find an ADHD medical professional on Klarity today, get your symptoms evaluated, and receive the proper treatment without leaving home.
